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Topic - H5N1/flu (other types) Posted: 06 Jul 2024 at 11:52pm By Dutch Josh |
< aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> Three key issues with #H5N1
1) mild disease means likely under detection. Severe disease shows up to hospitals; mild not so much
2) ongoing spillovers mean continuous chance for mutations/ human adaptation
3) human flu season gets closer by the day; human or animal w/ co-infection means risk of viral reassortment —> higher pandemic risk DJ https://flutrackers.com/forum/forum/flutrackers-high-pathogenic-h5n1-h1n08-h5n8-h5n6-h5n3-tracking-outbreaks-spread/749462-flutrackers-2016-global-h5n1-human-cases-list?view=stream or https://flutrackers.com/forum/forum/flutrackers-high-pathogenic-h5n1-h1n08-h5n8-h5n6-h5n3-tracking-outbreaks-spread/749462-flutrackers-2016-global-h5n1-human-cases-list?view=stream latest; In 2024 different H5N1 clades in humans; -Cambodia 6 human cases -US had 4 -Australia 1 Vietnam 1 So the first half-more or less-of 2024 did see 12 H5N1 human cases in 4 countries... In 2023-all of it !- we had 10 human cases; -Cambodia 6 -UK 2 -China 1 -Chile 1 Since H5N1 OFTEN !!!! is mild it may be very easy to miss ! The Case Fatality Ratio is not very realistic...The "killing potential" however may be very serious ! It is the background that matters ! H1N1-"Spanish Flu" had World War One -chaos-as a background...CoViD-immunity destruction-may give H5N1 (mixed with lots of other diseases and "politics gone stupid") all the room it needs ! |